NEW ORLEANS (AP) — Greg Desrosiers Jr. caught two scoring passes and ran for a touchdown, Seth Henigan became the American Athletic Conference's career passing leader, and Memphis defeated No. 18 Tulane 34-24 on Thursday night to close the Tigers' regular season..

The Green Wave turned the ball over three times deep in Memphis territory as their streak of regular-season conference victories ended at 17.

Two turnovers by Tulane came after long receptions at or inside the Memphis 10-yard line.

Tigers defensive back Kourtlan Marsh caused both fumbles, the first when he leveled Yulkeith Brown moments after his 40-yard catch. AJ Watts recovered at the 10 and returned it 37 yards, initiating a drive that ended with Desrosiers’ 29-yard touchdown run on third-and-4 to give Memphis (10-2, 6-2) a 27-10 lead.

In the fourth quarter, with Tulane trailing 27-17, Mario Williams fumbled at the Tigers 9 after hauling in a 55-yard pass and Marsh recovered.

Henigan completed 22 of 29 passes for 218 yards and two TDs without a turnover for Memphis, which totaled 454 yards against a Tulane defense that had allowed just nine points in its previous three games combined. Anderson rushed for 177 yards on 24 carries.

Henigan finished the game with 13,972 passing yards, breaking The American's old mark of 13,927 yards set by Holton Ahlers of East Carolina in 2022.

Mensah passed for 317 yards and two TDs, and Arnold Barnes ran for a 2-yard score.

Tulane gave up a touchdown on Memphis’ opening drive when Henigan hit Desrosiers for the first of his two touchdown catches — a 17-yard, leaping grab in tight coverage.

Tulane’s only lead came when Williams’ 7-yard TD catch made it 10-7 late in the first quarter.

But Desrosiers' 25-yard catch and run put the Tigers back in front for good in the second quarter.

The Tigers looked motivated and focused despite being out of the conference title picture. Offensively, they converted 10 of 16 third downs to help them surpass the 20-point plateau for a 39th straight game. The defense, meanwhile, was disruptive and opportunistic.

The Green Wave looked tight early. Receivers dropped several passes and Tulane’s normally productive run scheme did not appear to match up well with a Memphis run defense that ranked 18th nationally. Missed tackles on defense and trouble getting third-down stops made for a rough night.