HOUSTON -- Brady White threw for 341 yards and five touchdowns and ran for another score and No. 18 Memphis overcame a 10-point first-quarter deficit to beat Houston 45-27 on Saturday.



White completed 22 of 33 passes. Damonte Coxie caught four passes for 93 yards and two touchdowns, Antonio Gibson had four catches for 93 yards and a score, and Calvin Austin caught five passes for 81 yards and a touchdown.

Kenneth Gainwell finished with 99 rushing yards on 17 carries for Memphis, which outgained Houston 531-256. The Tigers (9-1, 5-1 American) have won five in a row. Houston (3-7, 1-5) lost its third straight.

Clayton Tune was 14 of 22 for 157 yards and a touchdown for the Cougars. Tune also had a 68-yard touchdown run, and Marquez Stevenson caught five passes for 89 yards and a touchdown.

Trailing 17-7 to begin the second quarter, Memphis outscored Houston 35-3 over the next two quarters. White found Coxie twice for touchdowns of 23 and 28 yards sandwiched around a White 14-yard touchdown run, a 14-yard touchdown pass from White to Austin and a 6-yard touchdown pass from White to Gibson.

The Memphis defense allowed 143 yards in the first quarter and 113 yards over the final three quarters. The Tigers finished with nine tackles for loss and three sacks. Memphis was 9 of 13 on third downs.

The Cougars continued to start off strong but had issues keeping it going again. Houston got into the red zone and settled for field goals twice. The Cougars were 3 of 10 on third downs.

Memphis is at USF on Saturday. Houston will be at Tulsa.