HOUSTON (AP) — Clayton Tune threw for 264 yards and a touchdown and ran for another score as No. 17 Houston extended its winning streak to 10 games with a 31-13 victory over Memphis on Friday night.

Tune tossed a 19-yard touchdown pass to Nathaniel Dell in the second quarter but was picked off twice, the first snapping a streak of 192 attempts without an interception. The QB also rushed for 59 yards, including a 20-yard touchdown as the Cougars (10-1, 8-0 American Athletic Conference) built a 21-3 lead at halftime.

Ta’Zhawn Henry rushed for 73 yards and a touchdown and Alton McCaskill rushed for 58 yards and a touchdown. Dell caught seven passes for 100 yards and Jeremy Singleton finished with five catches for 80 yards.

Houston gained 461 yards and was 8 of 15 on third downs.

Seth Henigan threw for 208 yards and a touchdown for Memphis (5-6, 2-5). Calvin Austin III had five catches for 103 yards. The Tigers gained 322 yards.

Asa Martin caught a 5-yard touchdown pass from Henigan, and David Kemp made a 22-yard field goal to cut the lead to eight early in the fourth quarter.

Following two straight three-and-out drives by Memphis, Dalton Witherspoon connected on a 34-yard field goal with 3:24 remaining to put Houston up by 11.

The Tigers closed within eight and had momentum, but could not finish, gaining 23 yards in the fourth quarter. Memphis finished 2 for 14 on third downs and 2 for 4 on fourth downs.

Houston's Marcus Jones had two interceptions, his fourth straight game with at least one pick. The Cougars were called for 11 penalties totaling 122 yards, including an unsportsmanlike conduct penalty on coach Dana Holgorsen.

Houston became the fourth American Athletic Conference team to finish conference play at 8-0, joining UCF's teams in 2013, 2017 and 2018.