BLOOMINGTON, Ind. — Charlotte finalized its non-conference schedule with a 52-14 loss to undefeated Indiana on Saturday.

Charlotte scored on a 13-yard run by CJ Stokes after an ineligible man downfield call took away its score a play before. A chance to double down came after the Hoosiers' holding call on their subsequent red-zone drive. It opened the door for a stop, possible field goal and lead if the 49ers could convert on the opposite end.

A defensive pass interference call on third down proved costly, instead, and gave way to a two-yard touchdown run to put the visitors back 17-7. Another comeback chance on the following drive, and after a 25-yard strike from Trexler Ivey to Isaiah Myers, was thwarted by Indiana's pair of big plays and Charlotte's facemask that paved the way for Kurtis Rourke's 12-yard touchdown scamper to go back up 24-14.

Penalties proved to be the 49ers' undoing.

Touchdowns on five consecutive drives included three in 15 minutes of game time that put the 49ers behind by 17 at halftime and 31 by the end of the third quarter. It was too late once they forced a punt to start the fourth.

The offense that helped Charlotte to a three-point deficit in the first half had a punt and turnover on downs in the same span to allow Indiana's clinching run.

The Hoosiers had eight rushing plays go at least 10 yards and another seven go at least 15 through the air. Their three pass plays of at least 37 yards were hard to overcome.