GREENVILLE, N.C. -- Quinton Flowers threw for two touchdowns and ran for another, and No. 17 USF extended its school-record winning streak to 10 by beating ECU 61-31 on Saturday.

D'Ernest Johnson rushed for 111 yards and two touchdowns, receiver Marquez Valdes-Scantling took an end-around 75 yards for a touchdown and caught a 4-yard scoring pass from Flowers, and Auggie Sanchez returned an interception 43 yards for a TD.

The Bulls (5-0, 2-0 American) overcame some rare struggles on defense and remained perfect under first-year coach Charlie Strong by scoring on 10 of the 12 possessions with the starting offense.

Flowers, The American's offensive player of the year in 2016, ran 16 yards for a touchdown and hit Tyre McCants for a 14-yard score. Darius Tice also had a 1-yard TD run for USF.

Thomas Sirk had two touchdown passes and two scoring runs to keep the Pirates (1-4, 1-1) in it. He hit Davon Grayson for a 31-yard TD and Stephen Baggett with a jump pass for a 2-yard TD on the final play of the first half.

Three of their first five opponents are in this week's Top 25 -- No. 12 Virginia Tech, No. 23 West Virginia and these Bulls.