KNOXVILLE, Tenn. (AP) — Joe Milton III threw for 156 yards and ran for 89 in the first half, leading No. 23 Tennessee to a 45-14 victory over UTSA on Saturday.

Milton played a key role in three early touchdowns for the Volunteers (3-1) — an 81-yard scoring run on the first play of the game and TD passes to Ramel Keyton and Kaleb Webb — as they took a 31-0 lead into halftime.

The Roadrunners (1-3) struggled without quarterback Frank Harris, who missed his second game with turf toe.

The offensive outburst was a welcome release for Tennessee, which had trouble the last two weeks in a win over Austin Peay and a loss to Florida. The Vols generated just 54 yards and no points in the third quarter, and then responded with two scores in the fourth.

Milton’s 81-yard scoring burst on the first play of the game was the longest scoring run by a quarterback in Tennessee history.

UTSA’s Tykee Ogle-Kellogg, who grew up in Alcoa, Tenn., 15 miles south of Neyland Stadium, caught a 43-yard TD pass. Vols center Cooper Mays missed his fourth straight game after having a medical procedure during training camp.

UTSA’s first turnover recovery this season was a strange one. Fourth down deep in Roadrunners territory in the first quarter, Lucas Dean’s punt was blocked. It rolled several yards and was touched by a Tennessee player. UTSA’s Kelechi Nwachuku recovered it.

The Roadrunners will try to get healthy and piece things together in time for their American Athletic Conference debut at Temple Oct. 7.